http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005097291-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-113
filingDate 2004-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7012ef774206fae621dd87f944528977
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publicationDate 2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2005097291-A
titleOfInvention W / O / W type composite emulsion
abstract PROBLEM TO BE SOLVED: It is known that a W / O / W type composite emulsion generally has poor stability. In particular, since it is difficult to encapsulate a water-soluble drug in the inner aqueous phase at a high encapsulation rate, the W / O / W type composite emulsion has not been used as a liquid. The present invention encloses a water-soluble drug that is poorly ingestible or easily decomposed by other components and factors at a high level to obtain a W / O / W type composite emulsion excellent in improving ingestibility and stabilizing active ingredients. For the purpose. [MEANS FOR SOLVING PROBLEMS] (1) Inner aqueous phase having a pH higher than the average pKa of components to be blended in the inner aqueous phase, (2) Polyglycerin fatty acid ester having an HLB value of 10 or less, or sucrose fatty acid ester having an HLB value of 10 or less (3) A W / O / W type composite emulsion comprising an outer aqueous phase having a pH lower than the average pKa of the components blended in the inner aqueous phase. [Selection figure] None
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014221802-A
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