| abstract |
Monoclonal antibodies for detection of ecstasy class compounds are provided. A novel analog of an ecstasy class compound linked at the methylenedioxy position shown in Formula 1, ie, derivatized, and a novel ecstasy class immunogen are included. The present invention also includes unique monoclonal antibodies and unique conjugates and tracers generated using MDO-conjugated MDMA immunogens. These antibodies, conjugates, and tracers are useful in immunoassays for the detection of ecstasy class compounds in biological fluids. (Wherein L is CO or CH 2 , X is NH or O, M is an aliphatic or aromatic carbon atom, Y is an active ester, isocyanate, etc., R 1 is H, CH 3 etc., R 2 is CH 3 Or C 2 H 5 , R 3 is a protecting group or H) [Selection figure] None |