| abstract |
[PROBLEMS] To provide a clinically useful analgesic agent having a non-opioid analgesic action, which has improved the drawbacks of morphine, and a novel muscle relaxant, antihypertensive agent, antiparkinsonian agent, and anti-Alzheimer's disease agent. An anti-ulcerative colitis agent or an anti-tobacco dependence agent is provided. [Solution] Bicycloheptane derivative (I) having the following general formula or a pharmacologically acceptable salt thereof. [In the formula, R represents a hydrogen atom, Y represents a> NH group, Z represents a furyl group or a tetrahydrofuryl group, which may be unsubstituted or substituted with a halogen atom, etc., and n represents 0 or 1-5. Means an integer. ] [Selection figure] None |