| abstract |
PROBLEM TO BE SOLVED: To administer infection with a pathogen consisting of inducing production of secretory IgA antibody in respiratory mucosal tissue specific to a virus or pathogen by administering double-stranded or single-stranded RNA which is a ligand of TLR To provide a method for protection, and further a secretory IgA antibody inducer. [Solution] A secretory IgA antibody inducer comprising double-stranded or single-stranded RNA as an active ingredient, and a virus or pathogen-specific IgA antibody can be obtained by administering double-stranded or single-stranded RNA. It is a method for inducing infection, and it is a method for protecting against infection by a pathogen, characterized by comprising inducing a secretory IgA antibody. A preferred double-stranded RNA is a secretory IgA antibody inducer that is Poly (I: C). [Selection figure] None |