| abstract |
An object of the present invention is to stabilize blood flow and allow perfusion of whole blood, increase the fixed density and purification efficiency of adsorbing groups to the level of a system using porous beads, and achieve a low-cost surface structure suitable for attaching functional groups to the membrane surface. The task is to achieve this through a labor-saving process. SOLUTION: Water permeability is 7500 ml / hr · kPa · m 2 or more, albumin permeability is 10% or more, and one or more acidic functional groups selected from a carboxyl group and a sulfonic acid group are used. Plasma separation for blood purification consisting of a hollow fiber membrane carrying one or more basic functional groups selected from grade 3, tertiary, quaternary amine and imine, and having a maximum pore diameter of 2 microns or less on the inner surface film. [Selection figure] None |