| abstract |
PROBLEM TO BE SOLVED: To provide a prophylactic or therapeutic agent that enhances fatty acid oxidation of skeletal muscle and is more effective for obesity, diabetes and abnormal lipid metabolism, and a method for using the same. SOLUTION: By combining or blending leptin with a drug such as metformin or AICAR that activates AMPK and a PPARĪ± activator such as a fibrate, the fatty acid oxidation of skeletal muscle is increased, obesity, diabetes, and lipids. An agent for preventing or treating metabolic disorders and a method for using the same are provided. [Selection figure] None |