abstract |
PROBLEM TO BE SOLVED: To provide an antineoplastic drug. Pyrimidine derivatives of formula (I) (wherein Q 1 , Q 2 , G and R 1 are as defined); and their pharmaceutically acceptable salts and in vivo hydrolysable esters. Their production methods, pharmaceutical compositions, and their use as inhibitors of cyclin-dependent serine / threonine kinases (CDK) and focal adhesion kinases (FAK). [Chemical 1] [Selection figure] None |