| abstract |
To provide a novel ceramide derivative having improved solubility and membrane permeability. In addition, to provide a novel anticancer agent with few side effects using the ceramide derivative thus obtained. A novel ceramide derivative represented by the following formulas (1) to (4). In particular, the N-lactilosphingosines of the formulas (1) and (2) exhibit high cell death-inducing activity against cancer cells and are useful as anticancer agents. In addition, the effective concentration was low for various cancer cell lines, indicating that the mechanism of action may be unique. [Selection figure] None |