| abstract |
PROBLEM TO BE SOLVED: To provide a technique for suppressing gene transcription, and a method for using the same, which is simpler and more widely applicable than conventional methods in a method for suppressing gene transcription. The peptide according to the present invention has an amino acid sequence represented by α 1 -Leu-β 1 -Leu-γ 1 -Leu, SEQ ID NO: 63 or SEQ ID NO: 66. However, in the formula, α 1 represents Asp, Asn, Glu, Gln, Thr or Ser, β 1 represents Asp, Gln, Asn, Arg, Glu, Thr, Ser or His, and γ 1 represents Arg, Gln, Asn, Thr, Ser, His, Lys or Asp is shown. Since this peptide has an extremely short size, its synthesis is simple, and transcription repression targeting a specific gene can be performed efficiently. [Selection figure] None |