| abstract |
PROBLEM TO BE SOLVED: To provide a method, a composition and a device capable of inducing proliferation of a nerve cell. Methods, compositions and devices suitable for the regeneration of nerve cells and nerve tissue and the repair of nerve defects are provided. A nerve replacement device comprising an artificial nerve replacement container comprising a composition containing a bone morphogenetic protein in an amount sufficient to promote astrocyte proliferation and a suitable matrix carrier, the bone morphogenic protein A neurological substitute device wherein is selected from the group consisting of BMP-2, BMP-4, BMP-5, BMP-6, BMP-7, BMP-2 / 6 heterodimer and BMP-2 / 7 heterodimer. [Selection figure] None |