abstract |
The present invention is in the field of medicinal chemistry and relates to pyrazole compounds that are protein kinase inhibitors (particularly inhibitors of ERK), compositions containing such compounds, and methods of use. These compounds are useful for treating cancer and other diseases that are alleviated by protein kinase inhibitors. Described herein are compounds having the formula (where R 1 , R 2 , T, n and Q are as described herein) and useful as protein kinase inhibitors. The compounds are useful for treating diseases in mammals that are alleviated by protein kinase inhibitors, particularly those diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease. |