http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004535452-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2002-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004535452-A |
| titleOfInvention | Arylboronic acids for the treatment of obesity |
| abstract | Disclosed are phenylboronic acid compounds represented by structural formula (I): Ar is a substituted or unsubstituted aryl group. Z and Z 'are independently -O-, -NH- or -S-. X is an electron withdrawing group. R is one or more amine, ammonium, ester, substituted or unsubstituted straight chain hydrocarbyl group containing a thioether or phenylene linking groups optionally, Y is -H, an amine, - [NH- (NH 2) q ] -NH 2, halogen, -CF 3, thiol, ammonium, alcohol, -COOH, -SO 3 H, phosphonium group covalently bonded to the terminal position of the -OSO 3 H or R. Each -NH- of-[NH- (NH 2 ) q ] -NH 2 is optionally N-alkylated or N, N-dialkylated, and is selected from-[NH- (NH 2 ) q ] -NH 2 -NH 2 is optionally, N- alkylated, N, N- dialkylated or N, N, is N- trialkylated. q is an integer from 2 to about 10, and r is an integer from 1 to about 5. R 1 and R 1 ′ are independently —H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group, or taken together to form an amine linking group — [N + (R 1a ) —] Is an NH 2 C 2 -C 5 substituted or unsubstituted alkylene group. Each R 1 in structural formula (I) is preferably -H. R 1a is —H, alkyl, substituted alkyl, phenyl or substituted phenyl. Also disclosed are methods of treating obesity in a subject by administering an effective amount of a compound represented by Structural Formula (I) and a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier or diluent. You. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015536324-A |
| priorityDate | 2001-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.