http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004535385-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004535385-A |
| titleOfInvention | Three-step conversion of protected taxane esters to paclitaxel |
| abstract | The present invention has the formula: Wherein P 1 is a hydrogenatable protecting group A method for producing paclitaxel from a protected coupled ester compound having the formula: wherein the 7-O-position and the 3'-N-position of the protected coupled ester compound are deprotected to form a first intermediate compound. Forming, benzoylating the first intermediate compound at the 3′-N-position, thereby forming a second intermediate compound, and converting the second intermediate compound to hydrogen with P 1 in the presence of an acid. The method relates to deprotecting by substituting. The present invention also provides compounds useful for producing paclitaxel. |
| priorityDate | 2001-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.