abstract |
An apparatus for delivering a bioactive substance includes a catheter and a balloon having microneedles or holes. In this device, the balloon can be provided with a polymer coating containing a bioactive substance, and the device can include a sheath surrounding the balloon. In one embodiment, the bioactive agent is delivered through a lumen in the microneedle. Another embodiment of the present invention is a device for delivering a bioactive substance, comprising a catheter having a balloon disposed thereon and a shock wave generator for generating a shock wave for delivering the bioactive substance to a lumen. It is. Also disclosed are methods for delivering a bioactive substance. |