http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004532046-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2002-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004532046-A |
| titleOfInvention | bcl-2 DNAzyme |
| abstract | The present invention specifically provides mRNA transcribed from a member of bcl-2 selected from the group consisting of bcl-2, bcl-xl, bcl-w, bfl-1, brag-1, Mcl-1 and A1. Provide a DNAzyme to cut. The DNAzyme has (a) the nucleotide sequence GGCTAGCTACAACGA (SEQ ID NO: 1), a catalytic domain that cleaves mRNA at any targeted purine: pyrimidine cleavage site, and (b) flanks the 5 'end of the catalytic domain. A binding domain, and (c) another binding domain adjacent to the 3 'end of the catalytic domain, both binding domains of the cleavage site to be catalyzed by the DNAzyme in the mRNA of the bcl-2 gene family. Hybridizes to and complementary to two regions adjacent to purine residues, wherein each binding domain is at least 6 nucleotides in length, and both binding domains are at least 14 nucleotides in total . |
| priorityDate | 2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.