http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004531271-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 |
| filingDate | 2002-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004531271-A |
| titleOfInvention | Methods for detecting diseases caused by chromosomal imbalance |
| abstract | The present invention provides a general method for detecting the presence of chromosomal abnormalities by using paralogous genes as internal controls in amplification reactions. The above method is fast, high-throughput, and easy for semi-automatic analysis. In one aspect, the method comprises providing a primer pair that can specifically hybridize to each paralogous gene set under conditions used in an amplification reaction such as PCR. Paralogous genes are preferably on different chromosomes, but can also be on the same chromosome (eg, to detect loss or gain of different chromosomal arms). By comparing the amount of amplification product produced, the relative dose of each gene can be determined and correlated with the relative dose of each chromosomal region and / or each chromosome where the gene is located. |
| priorityDate | 2001-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.