| abstract |
A blood-free metabolic support system for maintaining an organ (40) or tissue at a near normal metabolic rate is disclosed. The system comprises an organ chamber (32) containing a container (33) and a support (36) adapted to limit movement of the organ (40) within the container (33) during perfusion and / or transfer. Is used. The organ chamber (32) further includes a conduit (43) for receiving venous outflow of the perfusion solution and preventing contact of the external surface of the organ (40) with the venous outflow. The conduit (47) for receiving the organ product allows for collection of the organ product resulting from the functional organ (40) during perfusion. The use of the organ chamber (32) provides the necessary configuration for long-term maintenance of the organ for transplantation, resuscitation and active repair of organs suspected of having undergone warm ischemic injury, and transport of the removed organ. New or continuous synthesis of the components is supported. |