http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004529153-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
filingDate | 2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004529153-A |
titleOfInvention | Two-step conversion of protected taxane esters to paclitaxel |
abstract | The present invention is a process for preparing paclitaxel from a protected coupling ester compound having formula (I), wherein P 1 is a hydrogenatable protecting group, comprising the compound 7-O Deprotecting the-, 3'-N- and 2'-O-positions in the presence of an acid to form a first intermediate compound having formula (II) wherein HA is the acid described above. Forming and benzoylating the first intermediate compound at the 3'-N-position, thereby producing paclitaxel. |
priorityDate | 2001-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.