| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4713 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
| filingDate |
2002-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2004-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2004527248-A |
| titleOfInvention |
Method for producing catalytic antibody (variant), antigen for immunization and nucleotide sequence |
| abstract |
The present invention relates to the biotechnology, immunology, genetic engineering, and microbial and medical industries. It is an object of the present invention to develop a method for producing catalytic antibodies against proteins and peptides, in particular gp120, using animals with innate and induced autoimmune lesions. Various methods for making catalytic antibodies have also been disclosed. The method of the present invention creates a catalytic vaccine that, when injected into a patient, is both adsorbent to the antigen and has a destructive function, which can halt the progression of the disease. enable. The present invention discloses a method of the invention for autoimmunization of the animal strain SJL with a fusion protein comprising a typical peptide epitope that causes pathology in the animal with the gp120 protein fragment together with the catalytic antibody of interest. The present invention includes a method of immunizing an autoimmune animal with a highly reactive chemical composition that is capable of performing covalent selection of a catalytic clone containing a peptide fragment of the potential excised portion gp120. |
| priorityDate |
2001-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |