| abstract |
Methods, pharmaceutical compositions and compounds are provided for reducing weight (FIG. 5), modulating body fat metabolism, and reducing food intake in mammals. The compounds of the present invention include fatty acid ethanolamide compounds, homologs and analogs thereof, the prototype of which is oleoylethanolamide, an endogenous fatty acid ethanolamide. In one embodiment, the invention includes a method of reducing food intake in a mammal, the method comprising administering to the mammal a fatty acid alkanolamide, wherein the administering comprises administering to the mammal a fatty acid alkanolamide. It is an effective amount to reduce food intake in mammals. |