abstract |
The present invention relates to nucleic acid sequences involved in the regulation of apoptosis and reversion of tumors of the p53 pathway, as well as the proteins encoded by these nucleic acid sequences, as well as the control of tumor suppression and / or apoptosis in the biological chain of p53. A method based on the interaction between TSIP4 and TSIP2 for detecting, identifying and / or screening compounds for use in the treatment of cancer and certain neurodegenerative diseases associated with the dysfunction of thyroid. |