http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004525885-A
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2002-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004525885-A |
titleOfInvention | Purified hepatitis C virus envelope protein for diagnostic and therapeutic use |
abstract | The present invention relates to a method for purifying a recombinant HCV single or specific oligomer envelope protein selected from the group consisting of E1 and / or E2 and / or E1 / E2, comprising recombinantly expressing a protein. The present invention relates to a method characterized by performing a disulfide bond cleavage or reduction step using a disulfide bond cleaving agent when lysing a transformed host for isolation. The present invention also relates to compositions isolated by such methods. The invention also relates to diagnostic and therapeutic applications of these compositions. The present invention further relates to the use of HCV E1 proteins and peptides for the prognosis or monitoring of clinical outcome and / or clinical efficacy of HCV treatment. |
priorityDate | 2001-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1038.