abstract |
The present invention relates to preparations for the prevention of restenosis. Due to the fact that higher doses cause side effects, it is not possible to achieve sufficient active ingredient concentrations in the relevant area of the vessel wall using preparations for the prevention of restenosis known from the prior art. Can not. According to the present invention, at least one lipophilic and anti-thickening active ingredient with a partition coefficient of butanol and water of 0.5 or more is added to the preparation. A sufficient amount of the lipophilic active ingredient is rapidly absorbed by the vessel wall. This preparation may be dispensed by liquid or by capillary, and contains a contrast agent as normally required for contrast imaging, so that the delivery of the active ingredient to the blood vessels takes place without further complications. You can also. This preparation can also be applied to a catheter. |