| abstract |
The present invention relates to a compound of formula (I) [Chemical 1] [Wherein R is di-lower alkylamino, 1,2,3-triazol-1-yl, 1,2,3-triazol-2-yl or 1,2,4-triazol-4-yl; m represents an integer of 1 to 10, and n represents an integer of 0 to 10. ] Of α-amino-N-hydroxy-acetamide derivatives and salts thereof, processes for their preparation, pharmaceutical compositions containing the hydroxamic acid derivatives, use of such hydroxamic acid derivatives as pharmaceuticals, and the derivatives alone Or in combination with one or more other therapeutic agents for the treatment of abnormalities or diseases mediated by matrix degradable metalloproteinases (MMPs). |