abstract |
A new lipid molecule that releases nitric oxide is provided. The lipid molecules include (a) phosphoglyceride, (b) lipid having a sphingosine base as a skeleton, (c) monoacylglycerol, (d) diacylglycerol, (e) glycosylacylglycerol, and (f) R having 8 carbon atoms. As at least one branched aliphatic chain, a lipid molecule selected from the sterol compound represented by the structural formula (I) is provided, and the lipid molecule comprises (a) (I) site, (b) (I) site, And (c) a functional group having nitric oxide containing any of the (I) moieties. Furthermore, the present invention provides a lipid molecule forming method for forming a lipid molecule that releases nitric oxide. Various agents having lipid molecules that release nitric oxide, topical therapeutic liquids, and drug delivery systems are also disclosed. Furthermore, a method of therapeutically administering nitric oxide to a patient using a lipid molecule that releases nitric oxide, a method of treating or preventing various diseases, a method of promoting wound healing, and a cell present in an atheroma focus A method for reducing the number of is disclosed. |