| abstract |
The present invention provides compositions, therapeutic combinations and methods that include the following, which may be useful for treating vascular disease, diabetes, obesity and reducing plasma sterol levels: (a) at least one Bile acid sequestrants; and (b) at least one substituted azetidinone or substituted β-lactam sterol absorption inhibitor. In one embodiment, the present invention provides a composition comprising at least one (one or more) bile acid sequestrant and at least one (one or more) substituted azetidinone sterol absorption inhibitor or substituted β-lactam. The present invention relates to a composition containing a sterol absorption inhibitor, a pharmaceutical composition, a therapeutic combination, a kit and a treatment method using the same. |