| abstract |
A method for delaying the generation of polyps in the intestine of a subject and for preventing, inhibiting or treating cancer, comprising a peptide having an active domain of uroguanylin or a guanylate cyclase receptor GC-C in the intestine A method comprising administering to a subject a composition comprising an agonist peptide or compound of the invention in combination with a natural, natural-derived or chemically synthesized cyclooxygenase-2 inhibitor, preferably a selective cyclooxygenase-2 inhibitor. Disclose. |