http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004520426-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-353 |
| filingDate | 2001-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004520426-A |
| titleOfInvention | Preparation of warfarin sodium from warfarin sodium-2-propanol clathrate by solvent exclusion |
| abstract | The present invention is a method for producing warfarin sodium from a warfarin sodium 2-propanol inclusion compound by excluding a thermally non-decomposable solvent. This solvent exclusion is performed under conditions of controlled heat transfer, whereby 2-propanol is excluded from sodium warfarin 2-propanol clathrate without decomposition of sodium warfarin or its clathrate. Heating was performed on the clathrate in an active oven at a temperature of about 100 ° C. to about 170 ° C., in air or under an inert atmosphere, and at a partial pressure ranging from relatively reduced pressure to atmospheric pressure. . The present invention also relates to pure warfarin sodium prepared according to the method of the invention and to pharmaceutical compositions containing warfarin sodium. |
| priorityDate | 2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.