http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004520041-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2002-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004520041-A |
| titleOfInvention | New assay |
| abstract | A method for identifying a Nogo function modulator, comprising: (i) the following (a) to (c): (a) a BACE polypeptide; (b) a Nogo polypeptide; (c) a test agent [wherein the BACE polypeptide (a) is BACE, or a variant thereof capable of binding Nogo, or any fragment thereof, and polypeptide (b) is Nogo, or a variant thereof capable of binding BACE, or a derivative thereof. Any of the fragments] under the condition that the BACE polypeptide (a) and the Nogo polypeptide (b) can bind in the absence of the test drug (c); (ii) The method comprising monitoring the mediated activity; and (iii) thereby determining whether the test agent is a modulator of Nogo activity. Modulators identified by the methods of the invention and the use of such modulators in the manufacture of a medicament for treating a disorder responsive to modulation of Nogo activity, such as acute neuronal injury. |
| priorityDate | 2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 213.