http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004519689-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 |
| filingDate | 2002-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004519689-A |
| titleOfInvention | Methods for increasing the detection sensitivity of hybridized nucleic acids |
| abstract | The present invention provides a method for increasing the detection sensitivity of a hybridized nucleic acid immobilized on a substrate of a detection device for gene analysis by removing a nucleic acid probe that has not been hybridized from the substrate using a nuclease. . In the method of the present invention, the background signal generated by the single-stranded probe not hybridized to the target nucleic acid, or the signal due to non-specific binding between the target nucleic acid and the probe is reduced or eliminated, so that the nucleic acid hybridization Detection sensitivity and accuracy can be increased. In addition, the method of the present invention can minimize the loss of hybridized nucleic acid that occurs with conventional methods that reduce background signals by washing. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006114995-A1 |
| priorityDate | 2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.