| abstract |
The present invention relates to a class of heterocycles and metal complexes thereof, and in particular in the preparation of prodrugs which can be activated under hypoxia by enzymatic or therapeutic ionizing radiation in the treatment of cancer. Or the use of these compounds as prodrugs. The invention also relates to the use of these heterocycles and the corresponding metal complexes in the preparation of medicaments, as well as to compositions comprising these heterocycles or their metal complexes, and to methods of preparing these compounds. |