http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004517897-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 |
| filingDate | 2002-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004517897-A |
| titleOfInvention | Synthesis of temozolomide and analogs |
| abstract | The present invention relates to a novel process for the synthesis of the antitumor compound temozolomide and intermediates useful in this novel process. The present invention provides a process for the preparation of a compound of formula IA, wherein R is an alkyl group having 1 to 6 carbon atoms, the process comprising converting a compound of formula II to a soluble iodide And reacting with a suitable oxidizing / cyclizing agent in an inert medium, under an inert atmosphere, and at a temperature and for a time sufficient to produce a compound of Formula IA. |
| priorityDate | 2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.