| abstract |
The present invention relates to novel sulfamides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also relates to processes for the preparation of these compounds, pharmaceutical compositions containing one or more of these compounds, and related content, including their use as endothelin receptor antagonists in particular. But also. The present invention also relates to the above sulfamides for treating diseases related to the role of endothelin, in particular, for treating cardiovascular diseases such as hypertension, ischemia, vasospasm, and angina, and proliferative diseases such as cancer. , A pharmaceutical composition comprising conventional carrier substances and adjuvants. |