| abstract |
The present invention relates to at least one compound of the formula I (wherein R 1 , R 2 , R 3 , R 4 , n and X are as defined in claim 1) and their physiology. Pharmaceutically acceptable salts and / or solvates and a) at least one antithrombotic agent, or b) at least one calcium antagonist, or c) at least one prostaglandin or prostaglandin derivative. A pharmaceutical formulation comprising: Angina, high blood pressure, pulmonary hypertension, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), pulmonary heart, right heart failure, atherosclerosis, conditions with reduced cardiovascular patency, peripheral vascular disease, stroke The manufacture of a medicament for the treatment of bronchitis, allergic asthma, chronic asthma, allergic rhinitis, glaucoma, irritable bowel syndrome, tumors, renal failure and cirrhosis, and for the treatment of female sexual disorders. To the formulation. Embedded image |