http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004515492-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004515492-A |
| titleOfInvention | Guanidine and amidine derivatives as factor XA inhibitors |
| abstract | The present invention relates to compounds of formula (I), wherein R 0 , Q, X, Q ′, D, R 10 and V have the meanings as claimed. The compounds of the formula I are valuable pharmacologically active compounds. They have a strong antithrombotic effect and are suitable for the treatment and prevention of cardiovascular diseases such as, for example, thromboembolism or restenosis. These are reversible inhibitors of the blood clotting enzymes factor Xa (Fxa) and / or factor VIIa (FVIIa), generally such that the unwanted activity of factor Xa and / or factor VIIa is present or its treatment. Alternatively, it may be applied to conditions where inhibition of factor Xa and / or factor VIIa is intended for prevention. The invention further relates to a process for the preparation of the compounds of the formula (I), in particular their use as active ingredients in medicaments, and pharmaceutical preparations containing them. Embedded image |
| priorityDate | 2000-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.