abstract |
A novel method for promoting the dispersion of drug-containing particles in an aqueous medium is provided. According to this method, a solid dosage form of the drug is provided that incorporates a dispersing-promoting amount of an effervescent agent, wherein (a) the dosage form is suitable for swallowing without prior disintegration in water or in the mouth; (B) the amount of blowing agent is not sufficient to substantially promote disintegration of the dosage form in the aqueous medium. |