http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004513133-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-18 |
filingDate | 2001-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004513133-A |
titleOfInvention | Method for producing binding polypeptide and method for improving its therapeutic efficacy |
abstract | The present invention comprises at least about 9 × 10 7 k on the M -1 s -1 for the association of a ligand, and have therapeutic efficacy, provides a binding polypeptide or a functional fragment thereof. The invention also provides a method for determining the therapeutic efficacy of a binding polypeptide. The method comprises the steps of: (a) contacting the binding polypeptide with a ligand; (b) measuring the association rate for binding between the binding polypeptide and the ligand; and (c) the binding Comparing the association rate for the polypeptide to the association rate for the therapeutic control, wherein the relative association rate for the binding polypeptide compared to the association rate for the therapeutic control is Sex polypeptides exhibit a difference in therapeutic efficacy as a function of the difference between the association rates. |
priorityDate | 2000-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 408.