http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004511532-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 2001-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004511532-A |
titleOfInvention | 7-amino-2-alkylthiopteridin-4-ylamine for the treatment of chemokine-related diseases |
abstract | A pteridine compound of the formula (I) wherein R 1 , R 2 , R 3 and R 4 are specified in the claims, the process and the intermediates used in the process, and the medicaments containing them Compositions and their use in the treatment of psoriasis, rheumatoid arthritis, diseases where angiogenesis is associated with elevated CXCR2 chemokine levels, and inflammatory diseases such as COPD. The compounds are ligands for chemokine receptors, and include respiratory diseases (such as COPD, asthma, bronchitis, rhinitis, fibrous lung, pneumonia); bone and joint diseases (such as arthritis); skin diseases (such as psoriasis) Diseases of the gastrointestinal tract; other tissue and systemic diseases (such as multiple sclerosis, atherosclerosis, AIDS, type I diabetes, leprosy, sepsis, etc.); allograft rejection; cancer; Medical indications as described herein, including: disease; seizures; bone damage; skin ulcers; regenerative diseases and the like. |
priorityDate | 2000-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 179.