http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004511489-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2001-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004511489-A |
| titleOfInvention | Serine pro-ase small molecule inhibitors with polyhydroxyalkyl and polyhydroxycycloalkyl groups |
| abstract | The present invention relates to novel amidines and guanidines, their preparation and use as competitive inhibitors of trypsin-type serine proteases, in particular thrombin and complement proteases C1 and C1r. The invention also relates to medicaments containing said compounds as active ingredients, and further to their use as thrombin inhibitors, anticoagulants, complement inhibitors, anti-inflammatory agents. This novel composition is characterized by the binding of a serine protease having an amidine or guanidine function to an alkyl group having two or more hydroxyl functions, said alkyl group being derived from a sugar derivative. Some sugar structural components or products derived from sugars can thus be linked to one another. This principle of a linked sugar derivative gives an orally active compound. |
| priorityDate | 2000-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 324.