| abstract |
The present invention provides that R 1 is hydrogen or alkyl; R 2 is hydrogen or one or more alkyl groups; R 3 is R t or R t X—; wherein R t is hydrogen or Is an optionally substituted alkyl, aryl, aryl-alkyl, cycloalkyl or heterocyclyl; X is a linking group; R 4 is hydrogen or alkyl; The compounds are selective delta opioid receptor ligands and are therefore analgesic and anti-pain agents for different pain symptoms; immunosuppressants to prevent rejection in organ and skin transplants; anti-allergic and anti-inflammatory agents Cerebral cell protective agents; drugs and drugs to treat alcoholism, gastric secretion, diarrhea, cardiovascular and respiratory tract diseases, cough, psychosis and epilepsy Possibility Te is therapeutic utility of what is. |