| abstract |
A method of treating a patient suffering from peripheral vascular disease, peripheral neuropathy, or autonomic neuropathy by administering a cGMPＧPDE5 inhibitor, such as sildenafil. The method is particularly applicable to patients suffering from diabetic foot ulcers, Raynaud's phenomenon, CREST syndrome, erythromatosis, rheumatic diseases, diabetic retinopathy and onychomycosis. In accordance with the present invention, a cGMP PDE5 inhibitor may be administered as a prophylaxis to patients predisposed to developing peripheral vascular disease, peripheral neuropathy or autonomic neuropathy. |