http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004510778-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2001-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004510778-A |
| titleOfInvention | Platinum complexes as antitumor agents |
| abstract | The present invention relates to a platinum antitumor agent. In particular, the present invention relates to a cis-platinum complex having formula Ia or Ib, or a pharmaceutically acceptable salt thereof, wherein each A is independently an anion; each B is independently a halo, A hydroxy, carboxylate, carbamate or carbonate ester; Z is a substituted 5- or 6-membered heterocyclic moiety, wherein the substituted heterocyclic moiety further comprises a substituent, wherein the substituent is the same When tested under conditions, the steric hindrance of the Pt atom to the DNA strand of the tumor cell is more sterically hindered than unsubstituted heterocyclic moieties of the same structure. It is other than; and X, NH 3 or mono- - in some or dialkyl substituted NH 3; these are active against cancer cells, water solubility and activity are improved. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009501153-A |
| priorityDate | 2000-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.