| abstract |
Provided are immunomodulators comprising at least one Fc receptor ligand and at least one immunosuppressive factor, and methods for making and using the same. The immunomodulator may be in the form of a polypeptide or a chimeric antibody, and preferably incorporates immunosuppressive factors, including T cell receptor agonists or antagonists. The compounds and compositions of the present invention can be used to treat conditions associated with immune diseases such as allergy, transplant rejection, and autoimmune diseases including autoimmune diabetes, rheumatoid arthritis and multiple sclerosis. Can be used to selectively suppress the immune system. |