| abstract |
MC-4 and / or MC-3 receptor ligands and optical isomers, diastereomers or enantiomers thereof; pharmaceutically acceptable salts, hydrates and biologically hydrolysable esters thereof Amides or imides, wherein the ligand has the structure of formula (I): [Chemical 1] In the formula, R 2 , R 4 , R 4 ′ , R 5 , R 6 , R 6 ′ , R 7 , R 8 , R 8 ′ , R 9 , R 9 ′ , R 10 , Ar, Z 1 , Z 2 , Z 3 , X, B, D, p, q, r and s are as described in the description and claims. Also disclosed are pharmaceutical compositions comprising a ligand of formula (I) as described in the Detailed Description section of the specification, as well as methods for treating MC-4 / MC-3 receptor mediated diseases. |