| abstract |
Compounds of the general formula (I) or (II) containing novel piperazin-2-ones are described, including their pharmaceutically acceptable isomers, salts having activity against mammalian factor Xa , Hydrates, solvates, and prodrug derivatives. Compositions containing such compounds are also described. These compounds and compositions are useful in vitro or in vivo for preventing or treating a condition in a mammal characterized by unwanted thrombosis. |