abstract |
The present invention relates to a method for modulating angiogenesis and a method for inhibiting tumor progression by using a TWEAK receptor (Fn14) agonist. In particular, disclosed are methods for inhibiting angiogenesis. In one aspect, the invention provides a method of modulating angiogenesis, comprising the step of administering to a subject a therapeutically effective amount of a TWEAK receptor agonist. In another aspect, the invention provides a method of modulating angiogenesis, comprising administering a therapeutically effective amount of at least two Fn14 agonists and a pharmaceutically acceptable carrier. . |