Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
filingDate |
2001-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2004507449-A |
titleOfInvention |
Crystal structure of (AML1 Runt domain) / (CBFβ) heterodimer and ternary complex with DNA |
abstract |
The present invention relates to crystals comprising the AML1 Runt domain and / or CBFβ. The invention also provides a structural model of the interaction of AML1 Runt domain and / or CBFβ with DNA of AML1 Runt domain and the ability to bind to AML1 Runt domain and / or CBFβ and / or DNA binding of AML1 Runt domain. It relates to an improved means of ligand design that can adjust its capacity. |
priorityDate |
2000-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |