http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004507232-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004507232-A |
titleOfInvention | Methods for separating non-nuclear regulatory-mediated activity from steroid receptor-mediated nuclear transcription-regulating activity |
abstract | The present invention relates to a basic discovery in understanding the mechanism of action that is not mediated by steroid nuclear transcription control and its relationship to effects through steroid nuclear transcription control. (I) that effects that do not and do not through nuclear transcription control can be mediated by the same steroid receptor; (ii) both effects are induced by the ligand; (iii) rapid and That ligand-induced activation of the slowly adaptable ligand-binding domain exerts effects that are not through nuclear transcriptional regulation; (iv) steroids, which are typically the result of slower and stronger interactions Ligand-induced activation of the DNA binding domain of the receptor exerts an effect through nuclear transcriptional regulation; (v) the effect of ligand interaction without nuclear transcriptional regulation affects the selective response It has been discovered that ligand interactions can be related in this manner to effects through nuclear transcriptional regulation. The present invention also describes for the first time that certain steroids can induce effects that are not through nuclear transcriptional control through binding to an unrelated steroid receptor. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007306885-A |
priorityDate | 2000-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1938.