abstract |
The present invention provides a pharmaceutical composition comprising a synthetic or natural charged phospholipid, formulated in a dosage form for administration to a patient or added as a food additive. Negatively charged phospholipid compositions increase the total negative charge on vascular lipoproteins, enhance cholesterol clearance, regulate lipolytic enzyme function, delay prothrombin formation, and clear viral and bacterial particles. To assist. Thus, negatively charged lipid compositions can be administered to humans and animals to treat hyperlipidemia and blood coagulation disorders, and to reduce viral levels. Positively charged lipid compositions can be administered to delay clearance of the lipoprotein from the plasma compartment and prolong the activity of the drug associated with the lipoprotein. [Selection diagram] Fig. 1 |