| abstract |
[Object] To develop and provide a drug for improving a disease or tissue condition accompanied by a decrease in the amount of collagen in a tissue, and to provide a composition or the like for promoting collagen accumulation and / or suppressing the decrease in collagen accumulation. . The formula (I) (In the formula, X represents a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group, and n represents an integer of 0 to 3.) It has become possible to provide a composition and the like for promoting collagen accumulation and / or suppressing reduction, which contains a urea compound represented by [Selection diagram] None |